Basic Information
ID DDInter972
Drug Type small molecule
Molecular Formula C25H28N6O
Molecular Weight 428.529
CAS Number 138402-11-6
Description Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy.[L7459] Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry cough.[L7456,L7459] Irbesartan was granted FDA approval on 30 September 1997.[L7456,L7459]
ATC Classification C09CA04 C09DB05 C09DA04 C09DX07
IUPAC Name 2-butyl-3-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
InChI YOSHYTLCDANDAN-UHFFFAOYSA-N
Canonical SMILES CCCCC1=NC2(CCCC2)C(=O)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
Interactions with Irbesartan
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note