Basic Information
ID DDInter93
Drug Type small molecule
Molecular Formula C10H7Cl2N3O
Molecular Weight 256.088
CAS Number 68475-42-3
Description Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms.[L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997.[A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. [busulfan], [hydroxyurea]) and may be better tolerated.[A214274]
ATC Classification L01XX35
IUPAC Name 6,7-dichloro-1H,2H,3H,5H-imidazo[2,1-b]quinazolin-2-one
InChI OTBXOEAOVRKTNQ-UHFFFAOYSA-N
Canonical SMILES ClC1=CC=C2N=C3NC(=O)CN3CC2=C1Cl
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Anagrelide
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Multi-DRUG trade Multi-DRUG Drug type Warning Note