Drugs Information:
Hydrochlorothiazide
Basic Information
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ID | DDInter883 | |
Drug Type | small molecule | |
Molecular Formula | C7H8ClN3O4S2 | |
Molecular Weight | 297.739 | |
CAS Number | 58-93-5 | |
Description | Hydrochlorothiazide is the most commonly prescribed thiazide diuretic.[A185138] It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.[A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444] | |
ATC Classification | C09BX03 C03AX01 C03AB03 C09DX03 C03EA01 C09DX06 C09XA52 G01AE10 C09DX01 C03AA03 C09XA54 C09DX07 | |
IUPAC Name | 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide | |
InChI | JZUFKLXOESDKRF-UHFFFAOYSA-N | |
Canonical SMILES | NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1 | |
Useful Links | DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC |
Interactions with
Hydrochlorothiazide
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