Drugs Information:
Human C1-esterase inhibitor
Basic Information
![]() |
||
ID | DDInter869 | |
Drug Type | biotech | |
Protein Chemical Formula | None | |
Protein Average Weight | 68000.000 | |
CAS Number | - | |
Description | C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction of the immune system. The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several soft tissues or edema, which may last up to five days when untreated.[L16586, L16606] | |
ATC Classification | B06AC01 | |
Sequences | None | |
Useful Links | DrugBank PubChem Substance UniProtKB Wikipedia |
Interactions with
Human C1-esterase inhibitor
Filter:
Severity level | ID | Name | Mechanism | Detail |
---|
Interactions with diseases
Filter:
Severity level | Disease name | Text | References |
---|
Interactions with foods
Filter:
Severity level | Food name | Description | Management | Mechanism | References |
---|
Interactions with compound preparation
Multi-DRUG trade | Multi-DRUG | Drug type | Warning | Note |
---|