2D 3D
	ID	DDInter790
	Drug Type	small molecule
	Molecular Formula	C12H11ClN2O5S
	Molecular Weight	330.744
	CAS Number	54-31-9
	Description	Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative.[L7958] Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure.[L7961] It mainly works by inhibiting electrolyte reabsorption from the kidneys and enhancing the excretion of water from the body. Furosemide has a fast onset and short duration of action and has been used safely and effectively in both pediatric and adult patients.[A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential. In addition to oral formulations, the solution for intravenous and intramuscular administration is also available, which is typically limited to patients who are unable to take oral medication or for patients in emergency clinical situations.[L7958]
	ATC Classification	C03EB01 C03CA01 G01AE10 C03CB01
IUPAC Name	4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid
InChI	ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Canonical SMILES	NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O
Useful Links	DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC