Drugs Information:
Fluocinolone acetonide
Basic Information
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ID | DDInter751 | |
Drug Type | small molecule | |
Molecular Formula | C24H30F2O6 | |
Molecular Weight | 452.488 | |
CAS Number | 67-73-2 | |
Description | Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity.[T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676] | |
ATC Classification | S01CA10 D07BC02 S02BA08 C05AA10 S01BA15 D07AC04 S02CA05 D07CC02 | |
IUPAC Name | (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one | |
InChI | FEBLZLNTKCEFIT-VSXGLTOVSA-N | |
Canonical SMILES | [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO | |
Useful Links | DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC |
Interactions with
Fluocinolone acetonide
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