Basic Information
ID DDInter71
Drug Type small molecule
Molecular Formula C13H16N2O2
Molecular Weight 232.278
CAS Number 125-84-8
Description An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p454)
ATC Classification L02BG01
IUPAC Name 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
InChI ROBVIMPUHSLWNV-UHFFFAOYSA-N
Canonical SMILES CCC1(CCC(=O)NC1=O)C1=CC=C(N)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL
Interactions with Aminoglutethimide
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