Basic Information
ID DDInter708
Drug Type small molecule
Molecular Formula C16H18FN3O2
Molecular Weight 303.331
CAS Number 150812-12-7
Description Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy. FDA approved in June 10, 2011 under the name of ezogabine.
ATC Classification N03AX21
IUPAC Name ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate
InChI PCOBBVZJEWWZFR-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)NC1=C(N)C=C(NCC2=CC=C(F)C=C2)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Wikipedia ChEMBL ZINC
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Multi-DRUG trade Multi-DRUG Drug type Warning Note