Drugs Information:
Abciximab
Basic Information
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| ID | DDInter6 | |
| Drug Type | biotech | |
| Protein Chemical Formula | C6462H9964N1690O2049S48 | |
| Protein Average Weight | 145651.100 | |
| CAS Number | 143653-53-6 | |
| Description | Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules. It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells. | |
| ATC Classification | B01AC13 | |
| Sequences | >pdb|6V4P|C Chain C, Abciximab, heavy chain EVQLQQSGTVLARPGASVKMSCEASGYTFTNYWMHWVKQRPGQGLEWIGAIYPGNSDTSY IQKFKGKAKLTAVTSTTSVYMELSSLTNEDSAVYYCTLYDGYYVFAYWGQGTLVTVSAAS TKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGL YSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTH | |
| Useful Links | DrugBank PubChem Substance KEGG Drug PharmGKB Therapeutic Targets Database Wikipedia ChEMBL | |
Interactions with
Abciximab
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Interactions with diseases
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Interactions with foods
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Interactions with compound preparation
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