Basic Information
ID DDInter576
Drug Type small molecule
Molecular Formula C10H20N2S4
Molecular Weight 296.539
CAS Number 97-77-8
Description A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
ATC Classification P03AA04 P03AA54 N07BB01
IUPAC Name N,N-diethyl[(diethylcarbamothioyl)disulfanyl]carbothioamide
InChI AUZONCFQVSMFAP-UHFFFAOYSA-N
Canonical SMILES CCN(CC)C(=S)SSC(=S)N(CC)CC
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Disulfiram
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note