Basic Information
ID DDInter522
Drug Type small molecule
Molecular Formula C11H16N4O4
Molecular Weight 268.269
CAS Number 24584-09-6
Description An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.
ATC Classification V03AF02
IUPAC Name 4-[(2S)-1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione
InChI BMKDZUISNHGIBY-ZETCQYMHSA-N
Canonical SMILES C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Dexrazoxane
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Multi-DRUG trade Multi-DRUG Drug type Warning Note