Basic Information
ID DDInter51
Drug Type small molecule
Molecular Formula C18H21N5O2
Molecular Weight 339.392
CAS Number 850649-61-5
Description Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
ATC Classification A10BD13 A10BD09 A10BH04
IUPAC Name 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile
InChI ZSBOMTDTBDDKMP-OAHLLOKOSA-N
Canonical SMILES CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=C(C=CC=C2)C#N)C1=O
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB Wikipedia ChEMBL ZINC
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Multi-DRUG trade Multi-DRUG Drug type Warning Note