Basic Information
ID DDInter46
Drug Type small molecule
Molecular Formula C30H53N3O6
Molecular Weight 551.758
CAS Number 173334-57-1
Description Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension.[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.[L14018] Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents.[A203624]
ATC Classification C09XA54 C09XA53 C09DX02 C09XA02 C09XA52
IUPAC Name (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide
InChI UXOWGYHJODZGMF-QORCZRPOSA-N
Canonical SMILES COCCCOC1=C(OC)C=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=C1
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