Basic Information
ID DDInter454
Drug Type small molecule
Molecular Formula C20H21N
Molecular Weight 275.387
CAS Number 303-53-7
Description Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977.[A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.[A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
ATC Classification M03BX08
IUPAC Name dimethyl(3-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}propyl)amine
InChI JURKNVYFZMSNLP-UHFFFAOYSA-N
Canonical SMILES CN(C)CCC=C1C2=CC=CC=C2C=CC2=CC=CC=C12
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
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