Basic Information
ID DDInter416
Drug Type small molecule
Molecular Formula C22H17ClN2
Molecular Weight 344.837
CAS Number 23593-75-1
Description This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. Clotrimazole falls under the _imidazole_ category of _azole_ antifungals, possessing broad-spectrum antimycotic activity [A174094]. It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094]. The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well as athlete's foot [A174097].
ATC Classification D01AC01 A01AB18 G01AF02 G01AF20
IUPAC Name 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
InChI VNFPBHJOKIVQEB-UHFFFAOYSA-N
Canonical SMILES ClC1=CC=CC=C1C(N1C=CN=C1)(C1=CC=CC=C1)C1=CC=CC=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
Interactions with Clotrimazole
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Interactions with compound preparation
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