Basic Information
ID DDInter380
Drug Type small molecule
Molecular Formula C10H16N6S
Molecular Weight 252.339
CAS Number 51481-61-9
Description A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
ATC Classification A02BA51 A02BA01
IUPAC Name (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
InChI AQIXAKUUQRKLND-UHFFFAOYSA-N
Canonical SMILES CN\C(NCCSCC1=C(C)NC=N1)=N\C#N
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
Interactions with Cimetidine
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note