Basic Information
ID DDInter378
Drug Type small molecule
Molecular Formula C8H14N3O6P
Molecular Weight 279.187
CAS Number 113852-37-2
Description Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
ATC Classification J05AB12
IUPAC Name ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
InChI VWFCHDSQECPREK-LURJTMIESA-N
Canonical SMILES NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Cidofovir
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note