Basic Information
ID DDInter255
Drug Type small molecule
Molecular Formula C6H14O6S2
Molecular Weight 246.302
CAS Number 55-98-1
Description Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
ATC Classification L01AB01
IUPAC Name 4-(methanesulfonyloxy)butyl methanesulfonate
InChI COVZYZSDYWQREU-UHFFFAOYSA-N
Canonical SMILES CS(=O)(=O)OCCCCOS(C)(=O)=O
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Wikipedia ChEMBL ZINC
Interactions with Busulfan
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note