Basic Information
ID DDInter23
Drug Type small molecule
Molecular Formula C22H24N2O2
Molecular Weight 348.438
CAS Number 87848-99-5
Description Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia. Acrivastine is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D.
ATC Classification R06AX18
IUPAC Name (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid
InChI PWACSDKDOHSSQD-IUTFFREVSA-N
Canonical SMILES [H]\C(CN1CCCC1)=C(\C1=CC=C(C)C=C1)C1=CC=CC(=N1)C(\[H])=C(/[H])C(O)=O
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider Wikipedia ChEMBL ZINC
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