Basic Information
ID DDInter229
Drug Type small molecule
Molecular Formula C11H17BrN
Molecular Weight 243.163
CAS Number 59-41-6
Description Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.
ATC Classification C01BD02
IUPAC Name [(2-bromophenyl)methyl](ethyl)dimethylazanium
InChI AAQOQKQBGPPFNS-UHFFFAOYSA-N
Canonical SMILES CC[N+](C)(C)CC1=CC=CC=C1Br
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
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Multi-DRUG trade Multi-DRUG Drug type Warning Note