Basic Information
ID DDInter2136
Drug Type small molecule
Molecular Formula C13H19NO3
Molecular Weight 237.299
CAS Number 46817-91-8
Description Viloxazine is a selective norepinephrine reuptake inhibitor.[L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US, viloxazine was assigned an orphan drug designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and narcolepsy, the drug was never approved for these therapeutic indications. In April 2021, an extended-release formulation of viloxazine under the brand name QELBREE was approved by the FDA for the treatment of attention deficit hyperactivity disorder (ADHD).[A247985]
ATC Classification N06AX09
IUPAC Name 2-[(2-ethoxyphenoxy)methyl]morpholine
InChI YWPHCCPCQOJSGZ-UHFFFAOYSA-N
Canonical SMILES CCOC1=CC=CC=C1OCC1CNCCO1
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB Wikipedia ChEMBL
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Multi-DRUG trade Multi-DRUG Drug type Warning Note