Basic Information
ID DDInter1969
Drug Type small molecule
Molecular Formula C16H21N3O2
Molecular Weight 287.357
CAS Number 139264-17-8
Description Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including [almotriptan], [eletriptan], [frovatriptan], [naratriptan], [rizatriptan], and zolmitriptan.[A193791] Triptans can be administered alone or in combination with an NSAID like [naproxen], and represent the current "gold standard" for acute migraine treatment.[A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997. It is currently available in both tablet and nasal spray forms.[L12978]
ATC Classification N02CC03
IUPAC Name (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
InChI ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Canonical SMILES CN(C)CCC1=CNC2=CC=C(C[C@H]3COC(=O)N3)C=C12
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