Basic Information
ID DDInter1951
Drug Type small molecule
Molecular Formula C19H16O4
Molecular Weight 308.328
CAS Number 81-81-2
Description Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ability to cross the placental barrier during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification, and drug interactions have also been documented with warfarin use. Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of biologically active forms of various clotting factors in addition to several regulatory factors.
ATC Classification B01AA03
IUPAC Name 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
InChI PJVWKTKQMONHTI-UHFFFAOYSA-N
Canonical SMILES CC(=O)CC(C1=CC=CC=C1)C1=C(O)C2=C(OC1=O)C=CC=C2
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL
Interactions with Warfarin
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note