Basic Information
ID DDInter1750
Drug Type small molecule
Molecular Formula C34H44N4O4
Molecular Weight 572.750
CAS Number 1403254-99-8
Description Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.[L11476] Tazemetostat was first named in literature as EPZ-6438.[A190363] Tazemetaostat was granted FDA approval on 23 January 2020.[L11476]
ATC Classification L01XX72
IUPAC Name N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-5-[ethyl(oxan-4-yl)amino]-4-methyl-4'-[(morpholin-4-yl)methyl]-[1,1'-biphenyl]-3-carboxamide
InChI NSQSAUGJQHDYNO-UHFFFAOYSA-N
Canonical SMILES CCN(C1CCOCC1)C1=C(C)C(=CC(=C1)C1=CC=C(CN2CCOCC2)C=C1)C(=O)NCC1=C(C)C=C(C)NC1=O
Useful Links DrugBank PubChem Substance ChemSpider BindingDB Wikipedia ChEMBL ZINC
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