Basic Information
ID DDInter1665
Drug Type small molecule
Molecular Formula C17H26ClN
Molecular Weight 279.848
CAS Number 106650-56-0
Description Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
ATC Classification A08AA10
IUPAC Name {1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}dimethylamine
InChI UNAANXDKBXWMLN-UHFFFAOYSA-N
Canonical SMILES CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL
Interactions with Sibutramine
Filter:
Severity level ID Name Mechanism Detail
Interactions with diseases
Filter:
Severity level Disease name Text References
Interactions with foods
Filter:
Severity level Food name Description Management Mechanism References
Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note