Basic Information
ID DDInter1664
Drug Type small molecule
Molecular Formula C4H3F7O
Molecular Weight 200.055
CAS Number 28523-86-6
Description Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia.[L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient.[L42340] Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996.[A249885] Sevoflurane is three times more potent than [desflurane], but has lower potency compared to [halothane] and [isoflurane]. Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity.[A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.[A249885]
ATC Classification N01AB08
IUPAC Name 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane
InChI DFEYYRMXOJXZRJ-UHFFFAOYSA-N
Canonical SMILES FCOC(C(F)(F)F)C(F)(F)F
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Sevoflurane
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Multi-DRUG trade Multi-DRUG Drug type Warning Note