Basic Information
ID DDInter1619
Drug Type small molecule
Molecular Formula C16H24N2O
Molecular Weight 260.375
CAS Number 91374-21-9
Description Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711].
ATC Classification N04BC04
IUPAC Name 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one
InChI UHSKFQJFRQCDBE-UHFFFAOYSA-N
Canonical SMILES CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
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