Basic Information
ID DDInter1533
Drug Type small molecule
Molecular Formula C17H20N2S
Molecular Weight 284.419
CAS Number 60-87-7
Description Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29 March 1951.[A190177,L4000]
ATC Classification R06AD52 D04AA10 V03AB05 R06AD02
IUPAC Name dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
InChI PWWVAXIEGOYWEE-UHFFFAOYSA-N
Canonical SMILES CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL
Interactions with Promethazine
Filter:
Severity level ID Name Mechanism Detail
Interactions with diseases
Filter:
Severity level Disease name Text References
Interactions with foods
Filter:
Severity level Food name Description Management Mechanism References
Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note