Basic Information
ID DDInter1531
Drug Type small molecule
Molecular Formula C11H16ClN5
Molecular Weight 253.731
CAS Number 500-92-5
Description Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
ATC Classification P01BB01 P01BB51 P01BB52
IUPAC Name 1-[N'-(4-chlorophenyl)carbamimidamido]-N-(propan-2-yl)methanimidamide
InChI SSOLNOMRVKKSON-UHFFFAOYSA-N
Canonical SMILES CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Proguanil
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note