2D 3D
	ID	DDInter15
	Drug Type	small molecule
	Molecular Formula	C4H6N4O3S2
	Molecular Weight	222.245
	CAS Number	59-66-5
	Description	One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
	ATC Classification	G01AE10 S01EC01
IUPAC Name	N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
InChI	BZKPWHYZMXOIDC-UHFFFAOYSA-N
Canonical SMILES	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
Useful Links	DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC