Basic Information
ID DDInter1460
Drug Type small molecule
Molecular Formula C15H12N2O2
Molecular Weight 252.268
CAS Number 57-41-0
Description Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications such as bipolar disorder, retina protection, and wound healing.[A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal treatment, or adverse effects.[A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]
ATC Classification N03AB02 N03AB52
IUPAC Name 5,5-diphenylimidazolidine-2,4-dione
InChI CXOFVDLJLONNDW-UHFFFAOYSA-N
Canonical SMILES O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
Interactions with Phenytoin
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note