Basic Information
ID DDInter1427
Drug Type small molecule
Molecular Formula C20H31NO3
Molecular Weight 333.472
CAS Number 77-23-6
Description Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties. It is an active ingredient in over-the-counter cough suppressants in combination with guaifenesin and H1-receptor antagonists [A32160]. Pentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate.[L43942] Other forms of pentoxyverine citrate continue to be marketed.
ATC Classification R05DB05
IUPAC Name 2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate
InChI CFJMRBQWBDQYMK-UHFFFAOYSA-N
Canonical SMILES CCN(CC)CCOCCOC(=O)C1(CCCC1)C1=CC=CC=C1
Useful Links DrugBank ChEBI PubChem Substance ChemSpider BindingDB Wikipedia ChEMBL ZINC
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Multi-DRUG trade Multi-DRUG Drug type Warning Note