Drugs Information:
Pegvisomant
Basic Information
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| ID | DDInter1412 | |
| Drug Type | biotech | |
| Protein Chemical Formula | C990H1532N262O300S7 | |
| Protein Average Weight | 22129.000 | |
| CAS Number | 218620-50-9 | |
| Description | Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity. | |
| ATC Classification | H01AX01 | |
| Sequences | >DB00082 sequence FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPT PSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEG IQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIV QCRSVEGSCGF | |
| Useful Links | DrugBank PubChem Substance PharmGKB UniProtKB Therapeutic Targets Database Wikipedia ChEMBL | |
Interactions with
Pegvisomant
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Interactions with compound preparation
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