Basic Information
ID DDInter1359
Drug Type small molecule
Molecular Formula C15H11ClN2O2
Molecular Weight 286.713
CAS Number 604-75-1
Description Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism.[A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions.[L13895]
ATC Classification N05BA04
IUPAC Name 7-chloro-3-hydroxy-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
InChI ADIMAYPTOBDMTL-UHFFFAOYSA-N
Canonical SMILES OC1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC(Cl)=C2
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL
Interactions with Oxazepam
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