Basic Information
ID DDInter1300
Drug Type small molecule
Molecular Formula C14H10F3NO5
Molecular Weight 329.228
CAS Number 104206-65-7
Description Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
ATC Classification A16AX04
IUPAC Name 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione
InChI OUBCNLGXQFSTLU-UHFFFAOYSA-N
Canonical SMILES [O-][N+](=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C1C(=O)CCCC1=O
Useful Links DrugBank ChEBI PubChem Substance ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
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