Drugs Information:
Acenocoumarol
Basic Information
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| ID | DDInter13 | |
| Drug Type | small molecule | |
| Molecular Formula | C19H15NO6 | |
| Molecular Weight | 353.326 | |
| CAS Number | 152-72-7 | |
| Description | Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.[A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood. | |
| ATC Classification | B01AA07 | |
| IUPAC Name | 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one | |
| InChI | VABCILAOYCMVPS-UHFFFAOYSA-N | |
| Canonical SMILES | CC(=O)CC(C1=CC=C(C=C1)[N+]([O-])=O)C1=C(O)C2=CC=CC=C2OC1=O | |
| Useful Links | DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider PharmGKB Therapeutic Targets Database Wikipedia ChEMBL | |
Interactions with
Acenocoumarol
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