Drugs Information:
Acenocoumarol
Basic Information
|
||
ID | DDInter13 | |
Drug Type | small molecule | |
Molecular Formula | C19H15NO6 | |
Molecular Weight | 353.326 | |
CAS Number | 152-72-7 | |
Description | Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation.[A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients on acenocoumarol are prohibited from giving blood. | |
ATC Classification | B01AA07 | |
IUPAC Name | 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one | |
InChI | VABCILAOYCMVPS-UHFFFAOYSA-N | |
Canonical SMILES | CC(=O)CC(C1=CC=C(C=C1)[N+]([O-])=O)C1=C(O)C2=CC=CC=C2OC1=O | |
Useful Links | DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider PharmGKB Therapeutic Targets Database Wikipedia ChEMBL |
Interactions with
Acenocoumarol
Filter:
Severity level | ID | Name | Mechanism | Detail |
---|
Interactions with diseases
Filter:
Severity level | Disease name | Text | References |
---|
Interactions with foods
Filter:
Severity level | Food name | Description | Management | Mechanism | References |
---|
Interactions with compound preparation
Multi-DRUG trade | Multi-DRUG | Drug type | Warning | Note |
---|