Basic Information
ID DDInter128
Drug Type small molecule
Molecular Formula C28H31FN4O
Molecular Weight 458.570
CAS Number 68844-77-9
Description Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
ATC Classification R06AX11
IUPAC Name 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine
InChI GXDALQBWZGODGZ-UHFFFAOYSA-N
Canonical SMILES COC1=CC=C(CCN2CCC(CC2)NC2=NC3=CC=CC=C3N2CC2=CC=C(F)C=C2)C=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note