Basic Information
ID DDInter1239
Drug Type small molecule
Molecular Formula C16H24N2O2
Molecular Weight 276.374
CAS Number 7416-34-4
Description An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of clozapine. (From AMA Drug Evaluations Annual, 1994, p283)
ATC Classification N05AE02
IUPAC Name 3-ethyl-2-methyl-5-[(morpholin-4-yl)methyl]-4,5,6,7-tetrahydro-1H-indol-4-one
InChI KLPWJLBORRMFGK-UHFFFAOYSA-N
Canonical SMILES CCC1=C(C)NC2=C1C(=O)C(CN1CCOCC1)CC2
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL
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