Basic Information
ID DDInter1236
Drug Type small molecule
Molecular Formula C15H15NO2S
Molecular Weight 273.350
CAS Number 68693-11-8
Description Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA.
ATC Classification N06BA07
IUPAC Name 2-diphenylmethanesulfinylacetamide
InChI YFGHCGITMMYXAQ-UHFFFAOYSA-N
Canonical SMILES NC(=O)CS(=O)C(C1=CC=CC=C1)C1=CC=CC=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB PharmGKB Wikipedia ChEMBL
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Multi-DRUG trade Multi-DRUG Drug type Warning Note