Basic Information
ID DDInter1103
Drug Type small molecule
Molecular Formula C30H32Cl3NO
Molecular Weight 528.940
CAS Number 82186-77-4
Description Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infections acquired in chloroquine-resistant areas.
ATC Classification P01BF01
IUPAC Name 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol
InChI DYLGFOYVTXJFJP-MYYYXRDXSA-N
Canonical SMILES CCCCN(CCCC)CC(O)C1=C2C(=CC(Cl)=C1)\C(=C/C1=CC=C(Cl)C=C1)C1=C2C=CC(Cl)=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB PharmGKB Wikipedia ChEMBL
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Multi-DRUG trade Multi-DRUG Drug type Warning Note