Basic Information
ID DDInter1020
Drug Type small molecule
Molecular Formula C9H7Cl2N5
Molecular Weight 256.091
CAS Number 84057-84-1
Description Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries.[A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring. While it is indicated for epilepsy and bipolar disorders, there is evidence that lamotrigine could have some clinical efficacy in certain neuropathic pain states.[A849,A850]
ATC Classification N03AX09
IUPAC Name 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
InChI PYZRQGJRPPTADH-UHFFFAOYSA-N
Canonical SMILES NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
Useful Links DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Guide to Pharmacology Wikipedia ChEMBL ZINC
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