Drugs Information:
Lacosamide
Basic Information
|
||
ID | DDInter1014 | |
Drug Type | small molecule | |
Molecular Formula | C13H18N2O3 | |
Molecular Weight | 250.294 | |
CAS Number | 175481-36-4 | |
Description | Lacosamide is a functionalized amino acid that has activity in the maximal electroshock seizure test, and is indicated for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Recent studies indicate that Lacosamide only affects those neurons which are depolarized or active for long periods of time, typical of neurons at the focus of an epileptic seizure, as opposed to other antiepileptic drugs such as carbamazepine or lamotrigine which slow the recovery from inactivation and reduce the ability of neurons to fire action potentials. | |
ATC Classification | N03AX18 | |
IUPAC Name | (2R)-N-benzyl-2-acetamido-3-methoxypropanamide | |
InChI | VPPJLAIAVCUEMN-GFCCVEGCSA-N | |
Canonical SMILES | COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1 | |
Useful Links | DrugBank ChEBI PubChem Substance KEGG Drug ChemSpider BindingDB PharmGKB Wikipedia ChEMBL ZINC |
Interactions with
Lacosamide
Filter:
Severity level | ID | Name | Mechanism | Detail |
---|
Interactions with diseases
Filter:
Severity level | Disease name | Text | References |
---|
Interactions with foods
Filter:
Severity level | Food name | Description | Management | Mechanism | References |
---|
Interactions with compound preparation
Multi-DRUG trade | Multi-DRUG | Drug type | Warning | Note |
---|