Basic Information
ID DDInter1
Drug Type small molecule
Molecular Formula C14H18N6O
Molecular Weight 286.332
CAS Number 136470-78-5
Description Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
ATC Classification J05AR13 J05AR02 J05AR04 J05AF06
IUPAC Name [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol
InChI MCGSCOLBFJQGHM-SCZZXKLOSA-N
Canonical SMILES NC1=NC2=C(N=CN2[C@@H]2C[C@H](CO)C=C2)C(NC2CC2)=N1
Useful Links DrugBank ChEBI PubChem Substance KEGG Compound KEGG Drug ChemSpider BindingDB PharmGKB Therapeutic Targets Database Wikipedia ChEMBL ZINC
Interactions with Abacavir
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Interactions with compound preparation
Multi-DRUG trade Multi-DRUG Drug type Warning Note